All issues > Volume 38(9); 1995

Case Report

J Korean Pediatr Soc. 1995;38(9):1270-1275. Published online September 15, 1995.

Three Cases of Rotor Syndrome in Monozygotic Twin Brothers and Their Sister

Jin Hwa JH Jung¹, Jeong Ho JH Lee¹, Yong Sub YS Kim¹, Jong Dae JD Jo¹

¹Department of Pediatrics, Maryknoll Hospital, Busan, Korea

Abstract

We recently experienced three cases of Rotor syndrome in monozygotic twin brothers and their elder sister. The only clinical manifestation was persisting mild jaundice for several years. In all three cases serum bilirubin, mainly of direct reacting was increased with normal liver function and normal hepatic histology without pigmentation by needle liver biopsy. Indocyanine green test showed marked serum retention after 15 minutes and cholescintigraphy showed that liver was seen very faintly and persistent visualization of the cardiac pool and prominent kidney excretion after 60 minutes. A brief reviews of related literature was made.

Keywords :Rotor syndrome