All issues > Volume 39(3); 1996

Case Report

J Korean Pediatr Soc. 1996;39(3):423-430. Published online March 15, 1996.

A Case of Nonfamilial Generalized Gastrointestinal Juvenile Polyposis with Pancytopenia

Jong Ook JO Kim¹, Heung Pyo HP Kong¹, Kang Seo KS Park¹, Wan Seob WS Kim¹, Chun Hee CH Lee²

¹Department of Pediatrics, Presbyterian Medical Center, Chonju, Korea
²Department of Clinical Pathology Presbyterian Medical Center, Chonju, Korea

Abstract

In contrast to the child with a solitary juvenile polyp, generalized gastrointestinal juvenile polyposis have a much different clinical course. In generalized juvenile polyposis blood loss can be considerable and iron-deficiency anemia is a common observation. Although it is usually regarded as a benign condition, juvenile polyposis may predispose to cancer of the gastrointestinal tract. We experienced a case of nonfamilial generalized gastrointestinal juvenile polyposis with pancytopenia in a 15 year-old male patient who had hospitalized because of intermittent rectal bleeding with anemia for three years. Histological examination of polyps from affected patient revealed a spectrum of change from juvenile polyps, to juvenile polyps with adenomatous changes. Subtotal colectomy, rectal mucosectomy, and endorectal pull-through procedure were successfully performed. No complication has occured since the discharge. A brief review of related literatures is also presented.

Keywords :Juvenile polyposis, GI tract, Pancytopenia