All issues > Volume 39(5); 1996

Case Report

J Korean Pediatr Soc. 1996;39(5):722-726. Published online May 15, 1996.

Antiphospholipid Syndrome Presented with Pulmonary Embolism and Deep Venous Thrombosis in Child

Ran R Lee¹, Il Soo IS Ha¹, Hae Il HI Cheong¹, Yong Y Choi¹

¹Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea

Abstract

Antiphospholipid syndrome is a thrombotic disorder and the serologic marker of the syndrome is antiphospholipid antibody(lupus anticoagulant, anticardiolpin antibody, or both). In a 13-year-old girl who presented with dyspnea, pulmonary embolism and femoral vein thrombosis were demonstrated by lung scan and abdominal ultrasonography. She had 3 out of 11 criteria for the diagnosis of SLE, such as thrombocytopenia, positive antinuclear antibody, low C3 and high anti-ds-DNA Ab, but did not meet whole criteria. And lupus anticoagulant was positive. She was treated with anticoagulants(heparin and wafarin) and prednisolone. Antiphospholipid antibody(lupus anticoagulant and anticardiolipin antibody) should be checked in children with thrombosis occurring without a known predisposing cause.

Keywords :Antiphospholipid syndrome, Pulmonary embolism, Deep vein thrombosis