All issues > Volume 40(8); 1997

Case Report

J Korean Pediatr Soc. 1997;40(8):1173-1177. Published online August 15, 1997.

A Case of Neuronal Heterotopia

Jeong Hae JH Joo¹, Eun Joo EJ Seok¹, Min Jeong MJ Kim¹, Son Sang SS Seo¹

¹Department of Pediatrics, Il Sin Christian Hospital, Pusan, Korea

Abstract

Neuronal migrational disorders of the brain represent abnormalities in the formation of the neocortex caused by faulty migration of the subependymal neuroblasts. The neuroblasts normally migrate between the sixth and 15th gestational week and in doing so form the six-layered neocortex. When the migration does not occur in a normal fashion the resultant brain anomalies include lissencephaly, pachygyria, schizencephaly, hemimegalencephaly, heterotopia, and polymicrogyria. Neuronal heterotopia is a collection of nerve cells in abnormal locations as a result of arrest of their radial migration, improper formation, or destruction of the radial glial fiber. We reported a case of neuronal heterotopia with brief review of related literatures.

Keywords :Neuronal heterotopia, Agenesis of corpus callosum, Neuronal migration disorders