All issues > Volume 40(11); 1997

Original Article

J Korean Pediatr Soc. 1997;40(11):1537-1543. Published online November 15, 1997.

Comparison of Antimicrobial Susceptibility of Nosocomial and Community-Acquired Pathogens in Children of Medium-Sized Hospital

Kil Soo KS Joung¹, Jae Kook JK Cha¹, Kon Hee KH Lee¹, Hye Sun HS Yoon¹, Wonkeun Wk Song²

¹Department of Pediatrics, College of Medicine, Hallym University, Seoul, Korea
²Department of Clinical Pathology, College of Medicine, Hallym University, Seoul, Korea

Abstract

Purpose
: We evaluated the identification and antimicrobial susceptibility patterns of nosocomial and community-acquired pathogens in children of the medium-sized hospital.
Methods
: The 357 bacterial strains isolated from Pediatric department of Dongsan Sacred Heart Hospital were examined the species identification and antimicrobial susceptibility test during the period of March to October 1996.
Results
: Fifty three strains(15%) of 357 strains were nosocomial pathogens. A half of Enterococcus faecium is nosocomial pathogens. As a rule, Antimicrobial resistance of nosocomial pathogens were higher than those of community-acquired pathogens. Enterococcus sp. isolated from nosocomial infection were significantly less susceptible than those from community-acquired infection to imipemem(P < 0.05). Escherichia coli isolated from nosocomial infection were significantly less susceptible than those from community-acquired infection to amoxicillin/clavulanate, cefuroxime, cefoxitin, ceftazidime, and aztreonam(P < 0.05). Klebsiella pneumoniae isolated from nosocomial infection were significantly less susceptible than those from community-acquired infection to cephalothin, cefuroxime, cefotaxime, aztreonam, tobramycin, gentamicin, and co-trimoxazole(P < 0.05).
Conclusions
: In medium-sized hospital, the rate of antimicrobial resistance to nosocomial pathogens was higher than community-acquired pathogens. The regular reports of the susceptibility patterns of nosocomial and community-acquired pathogens would be useful to improve the effects of empirical antimicrobial therapy.

Keywords :Nosocomial infection, Community-acquired infection, Medium-sized hospital