All issues > Volume 41(6); 1998

Case Report

J Korean Pediatr Soc. 1998;41(6):845-849. Published online June 15, 1998.

A Case of Neonatal Hyperthyroidism with Unilateral Ear Anomaly

Kwang Ok KO Chung¹, Na Yeon NY Kim¹, Sung Min SM Cho¹, Dong Seok DS Lee¹, Doo Kwun DK Kim¹, Sung Min SM Choi¹

¹Department of Pediatrics, College of Medicine, Dongguk University, Kyongju, Korea

Correspondence Kwang Ok KO Chung ,Email: 1

Abstract

Neonatal hyperthyroidism is a very rare disorder occurring typically in the offspring of patients with Graves' disease or chronic thyroiditis. It is caused by the transplacental passage of thyroid stimulating antibodies(TSAb) from the mother to the fetus. There has been few reports of neonatal hyperthyroidism associated with congenital anomalies. We experienced a case of neonatal hyperthyroidism with unilateral microtia and agenesis of external auditory canal in a female neonate born to a mother who had euthyroid but with a thyroid stimulating antibody. The patient was presented with unusual alertness, tachycardia, tachypnea, watery diarrhea, periorbital swelling and exophthalmos. Diagnosis was made by thyroid function tests and TSAb. She was treated with Lugol solution, PTU and propranolol. New she is 6 months old and in good condition with no symptoms of hyperthyroidism.

Keywords :Neonatal hyperthyroidism, Thyroid-stimulating antibody(TSAb), Ear anomaly