All issues > Volume 41(10); 1998

Case Report

J Korean Pediatr Soc. 1998;41(10):1424-1429. Published online October 15, 1998.

A Case of Congenital Self-Healing Reticulohistiocytosis

Taek Sun TS Kim¹, Chang Wan CW Kim¹, Eun Ryoung ER Kim¹, You Mee YM Kang¹, Kye Yong KY Song²

¹Department of Pediatrics, Sung-Ae General Hospital, Seoul, Korea
²Department of Pathology, School of Medicine, Chung-Ang University, Seoul, Korea

Correspondence Eun Ryoung ER Kim ,Email: 1

Abstract

Congenital self-healing reticulohistiocytosis(CSHR) is a rare variant of cutaneous reticulohistiocytosis. We report a newborn who had about 25 reddish brown papulonodular lesions on whole body at birth. No extracutaneous involvement was found. All skin lesions involuted within 4 months spontaneously. Biopsy of a skin lesion showed marked aggregated histiocytic infiltration with some eosinophils. S-100 protein and lysozyme were positive. Electron microscopy revealed numerous dense bodies, often with a myelin-like core and some Birbeck granules. We described a detailed clinical features of this case and reviewed the literatures.

Keywords :Congenital self healing reticulohistiocytosis, Langerhans cell, Birbeck granule, Laminated body