All issues > Volume 42(1); 1999

Case Report

J Korean Pediatr Soc. 1999;42(1):128-132. Published online January 15, 1999.

A Case of Acute Myeloblastic Leukemia Transformed from Transient Myeloproliferative Disorder with Down Syndrome

Jae Eun JE Lee¹, Seung Woo SW Baeck¹, Wan Seob WS Kim¹, Chun Hee CH Lee²

¹Department of Pediatrics, Presbyterian Medical Center, Chonju, Korea
²Department of Clinical Pathology, Presbyterian Medical Center, Chonju, Korea

Abstract

Individuals with Down syndrome have a high incidence of hematologic diseases such as transient myeloproliferative disorder(TMD) & acute leukemia. Because it is difficult to distinguish TMD from acute myeloblastic leukemia, the diagnosis in neonate, who have Down syndrome, should be made with extreme caution. TMD usually undergoes spontaneous remission within a few months, but acute leukemia can develope after remission of TMD. We now report a case of acute myeloblastic leukemia that was a transformed TMD with Down syndrome.

Keywords :Transient myeloproliferative disorder, Down syndrome, Acute myeloblastic leukemia