All issues > Volume 42(11); 1999

Case Report

J Korean Pediatr Soc. 1999;42(11):1574-1578. Published online November 15, 1999.

Dapsone in a Case with Chronic Recurrent Henoch-Schönlein Purpura

Jin J Choi¹, Soo Jung SJ Lee¹, Dae Kyun DK Koh¹

¹Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea

Correspondence Soo Jung SJ Lee ,Email: 1

Abstract

The most clearly delineated condition with prominent cutaneous leukocytoclastic vasculitis which presents to a pediatrician is Henoch-Schönlein purpura. There is general agreement that in Henoch-Schönlein syndrome the skin manifestations have a very benign long-term course and that corticosteroids are of little value. Dapsone appears to be of special value in diseases characterized by an accumulation of polymorphonuclear neutrophils notably leukocytoclastic vasculitis. In the pediatric literature, however, no information is available on the use of this sulfone in Henoch- Schönlein purpura. We report a case of Henoch-Schönlein purpura in a 14-year-old female patient who presented with chronic recurrent skin manifestation and responded to dapsone for two years.

Keywords :Henoch-Schönlein Purpura, Leukocytoclastic vasculitis, Dapsone