All issues > Volume 43(6); 2000

Case Report

J Korean Pediatr Soc. 2000;43(6):846-850. Published online June 15, 2000.

A Case of Chronic Granulomatous Disease in which Enterococci were Observed in Culture

Kyunglae KL Cho¹, Jeonghee JH Kim¹, Eunjeong EJ Kim¹, Churwoo CW Yoo¹, Chunsoo CS Kim¹, Unseok US Nho¹, Chulkyu CK Kim¹

¹Department of Pediatrics, College of Medicine, Sung Kyun Kwan University, Masan Samsung Hospital, Masan, Korea

Abstract

Chronic granulomatous disease(CGD) is a genetically inherited disorder caused by the failure of phagocytic cells to produce superoxide. It is characterized by frequent and uncontrollable infection which often lead to death in early childhood. The first clinical signs may be confined to skin and manifest themselves as abscesses, pyoderma, eczema or draining sinuses. The disease was first reported in 1957 and thereafter the biomolecular mechanism has been found. The first report in Korea was an autopsy case in 1979 and since then there have been a few case reports. This disease is diagnosed by symptoms, such as high fever, cervical lymphadenopathy, skin nodule, lung field infiltration, periumbilical abscess, liver abscess, pyoderma and pericordal abscess. The pathogen here were catalase producing bacteria and fungi. However, we have experienced a case of CGD, in which symptoms were perianal, scrotal abscesses and lung field nodular infiltration. In this case the pathogen was found as a catalase negative Enterococcus.

Keywords :Chronic granulomatous disease, Catalase negative Enterococcus