All issues > Volume 43(8); 2000

Case Report

J Korean Pediatr Soc. 2000;43(8):1149-1152. Published online August 15, 2000.

A Case of Fixed Drug Eruption Due to Acetaminophen

Eui Jeong EJ Min¹, Dae Hyun DH Lim¹, Jung Hee JH Kim¹, Seung Won SW Choi², Byong Kwan BK Son³

¹Department of Pediatrics, College of Medicine, Inha University, Korea
²Department of Internal Medicine, College of Medicine, Inha University, Korea
³Department of Pediatrics, College of Medicine, Inha University, Korea

Abstract

Fixed drug eruption normally presents as single or multiple sharply demarcated erythematous lesions that recur at the same location upon re-exposure to the offending agent. When the acute inflammation subsides, it often leaves residual hyperpigmentation. Commonly implicated substances are phenolphthalein, barbiturates, sulfonamides, tetracyclines, salicylates, gold and pyrazolone derivatives. Despite frequent use of acetaminophen, drug eruptions, especially fixed drug eruptions, due to acetaminophen are extremely rare. We report here a childhood case of fixed drug eruption caused by acetaminophen, which is extensively used as an over-the-counter drug, as well as in medical therapy.

Keywords :Acetaminophen, Fixed drug eruption