All issues > Volume 43(9); 2000

Case Report

J Korean Pediatr Soc. 2000;43(9):1294-1299. Published online September 15, 2000.

A Case of Sporadic Caffey`s Disease(Infantile Cortical Hyperostosis) Without Mandibular Involvement

Byoung Lae BL Oh¹, Seung Woo SW Paik¹, Wan Seob WS Kim¹

¹Department of Pediatrics, Presbyterian Medical Center, Chonju, Korea

Abstract

Caffey`s disease(infantile cortical hyperostosis) is an uncommon benign and self limited disorder of unknown etiology, affecting the skeleton and its contiguous fasciae and muscles. Its occurrence in isolated cases or in multiple members in families suggests the existence of two different forms, namely a sporadic form and a familial form. The tibia is the predominant bone known to be affected in the familial form, while the mandible is mostly affected in the sporadic form. This benign and self-limited disorder has rarely late recurrence or persistence of symptoms with deformity. The patient in this case had immediate and complete resolution of her symptoms while receiving acetaminophen with no recurrent bone formation during treatment with antiinflammatory drugs. We describe sporadic, nonfamilial Caffey`s disease, affecting both radii and tibiae, but not involving the mandibular in a 4-month-old female infant.

Keywords :Caffey`s disease, Infantile cortical hyperostosis, Sporadic, Familial