All issues > Volume 44(7); 2001

Case Report

J Korean Pediatr Soc. 2001;44(7):823-826. Published online July 15, 2001.

A Case of Aseptic Meningitis Following Administration of Intravenous Immunoglobulin in A Patient with Idiopathic Thrombocytopenic Purpura

Su Jin SJ Kim¹, Ji Eun JE Kim¹, Hei Won HW Hwang¹, Ji Sun JS Mok¹, Dong Seok DS Lee¹, Doo Kwun DK Kim¹, Sung Min SM Choi¹, Woo Taek WT Kim²

¹Department of Pediatrics, College of Medicine, Dongguk University, Kyung-ju, Korea
²Department of Pediatrics, College of Medicine, The Catholic University of Korea, Taegu, Korea

Abstract

Intravenous immunoglobulin(IVIG) has been widely used to treat idiopathic thrombocytopenic purpura in childhood. Aseptic meningitis has been reported as a rare complication of IVIG therapy. This report is on an 11 year-old boy with ITP who suffered from aseptic meningitis following the administration of IVIG. He was given 1 g/kg of IVIG for 2 days, and on the fourth day after the administration of IVIG, he experienced headache, vomiting and fever. Cerebrospinal fluid showed 400/mm3 white cells with 96% segmented neutrophils and 1% lymphocytes. The symptoms subsided within 8 days of admission.

Keywords :Intravenous immunoglobulin, Aseptic meningitis