All issues > Volume 44(8); 2001

Original Article

J Korean Pediatr Soc. 2001;44(8):881-885. Published online August 15, 2001.

M-mode Echocardiographic Abnormalities in Infants of Diabetic Mothers

Myung Chul MC Hyun¹

¹Department of Pediatrics, School of Medicine, Kyungpook National University, Taegu, Korea

Abstract

Purpose
: The purpose of this study was to evaluate M-mode echocardiographic abnormalities in infants of relatively well controlled diabetic mothers and to determine the timing of spontaneous regression.
Methods
: Echocardiographic study was prospectively carried out in 9 neonates born to diabetic mothers(infants of diabetic mothers, IDM) and 6 newborn infants(control) matched for weight and age. And the study were repeated in 3 of 9 IDM(follow up) after 3 to 16 months. M-mode echocardiography included measurements of left and right ventricular free wall and interventricular septal thickness and ventricular diastolic and systolic dimensions; LV function is expressed as shortening fracion.
Results
: Interventricular septal thickness(0.56?.13 vs 0.32?.09) and STd/PWTd(2.04?.60 vs 1.19?.44) were significantly higher in infants of diabetic mothers than in control newborn infants. Follow up measurements showed regression of interventricular septal thickness(2.13?.58 vs 1.02?.66/M2) but no significant improvement in STd/PWTd(2.04?.60 vs 1.67?.25) compared with initial measurements.
Conclusion
: M-mode echocardiographic abnormalities including interventricular septal hypertrophy and high STd/PWTd were observed even in infants of relatively well controlled diabetic mothers and may persist for a somewhat longer period.

Keywords :Echocardiographic abnormalities, Infants of diabetic mothers, Spontaneous regression