All issues > Volume 45(5); 2002

Case Report

J Korean Pediatr Soc. 2002;45(5):664-668. Published online May 15, 2002.

Hemophagocytic Syndrome with Kawasaki Disease and Peripheral Gangrene

Hwa Jun HJ Yun¹, Ko Woon KW Jeon¹, Hwang Min HM Kim¹, Seok Won SW Park¹, Young Y Uh²

¹Department of Pediatrics, Yonsei University, Wonju College of Medicine, Wonju, Korea
²Department of Clinical Pathology, Yonsei University, Wonju College of Medicine, Wonju, Korea

Correspondence Hwang Min HM Kim ,Email: khm9120@wonju.yonsei.ac.kr

Abstract

A twenty six months-old boy developed hemophagocytic syndrome during the course of Kawasaki disease. Despite the appropriate treatment modalities for Kawasaki disease, he developed thrombocytopenia, hepatomegaly, high-grade fever, hypertriglyceridemia, peripheral gangrene, and evidence of hemophagocytosis in bone marrow biopsy. Although the course was stormy, he responded well to a combination therapy of corticosteroid and etoposide.

Keywords :Etoposide, Hemophagocytic syndrome, Bone marrow biopsy, Kawasaki disease, Peripheral gangrene