All issues > Volume 45(9); 2002

Case Report

J Korean Pediatr Soc. 2002;45(9):1150-1154. Published online September 15, 2002.

Two Cases of Wolff-Parkinson-White Syndrome in a Family

Chan Uhng CU Joo¹, So Hee SH Lim¹, Pyung Han PH Hwang¹

¹Department of Pediatrics, Medical School, Chonbuk National University, Institute of Cardiovascular Research, Jeonju, Korea

Correspondence Chan Uhng CU Joo ,Email: joocu@moak.chonbuk.ac.kr

Abstract

Wolff-Parkinson-White(WPW) syndrome is characterized by electrographic evidence of ventricular preexcitation, which predisposes to supraventicular arrhythmias. Familial occurrence of WPW syndrome is uncommon. We observed two affected siblings in a family. Five members of the family underwent 12-lead electrocardiography and echocardiography. Although known genetic abnormality of the 7q34-q36(PRKAG2) for the familial WPW syndrome was evaluated, the mutation was not detected in this family. Other unknown mutations responsible for this familial WPW syndrome were suggested.

Keywords :Wolff-Parkinson-White syndrome, Family