All issues > Volume 45(9); 2002

Case Report

J Korean Pediatr Soc. 2002;45(9):1165-1169. Published online September 15, 2002.

A Case of Satoyoshi Syndrome Presented with Progressive Muscular Spasm and Alopecia

Kyung Ran KR Son¹, Jin Hwa JH Kook¹, Byung Ju BJ Kim¹, Sung Jin SJ Kim², Jae Sook JS Ma¹

¹Department of Pediatrics, Chonnam National University, Medical School, Gwangju, Korea
²Department of Dermatology, Chonnam National University, Medical School, Gwangju, Korea

Correspondence Byung Ju BJ Kim ,Email: kimbj@chonnam.ac.kr

Abstract

Satoyoshi syndrome(generalized Komuragaeri disease) is a rare disorder of unknown cause, characterized by progressive, painful, intermittent muscle spasms and alopecia. Endocrinopathy with amenorrhea, secondary skeletal abnormalities, and diarrhea or unusual malabsorption are frequently seen. It seems that autoimmunity may play a role in its pathogenesis. We report a 13-year-old girl with characteristic manifestations of the syndrome. She was treated with intravenous gammaglobulin and Prednisolone. Painful muscle cramps were gradually improved, but the scalp condition did not change. Satoyoshi syndrome should be considered in children with unexplained muscle spasms and alopecia.

Keywords :Satoyoshi syndrome, Muscle spasm, Alopecia