All issues > Volume 45(9); 2002

Case Report

J Korean Pediatr Soc. 2002;45(9):1170-1174. Published online September 15, 2002.

A Case of Centronuclear Myopathy

Yun Hee YH Kim¹, Yun Hee YH Kim¹, Young Se YS Kwon¹, Young Se YS Kwon¹, Dae Hyun DH Lim¹, Dae Hyun DH Lim¹, Yong Hun YH Jun¹, Yong Hun YH Jun¹, Soon Ki SK Kim¹, Soon Ki SK Kim¹, Young Jin YJ Hong¹, Young Jin YJ Hong¹, Byong Kwan BK Son¹, Byong Kwan BK Son¹, Hae Seung HS Han², Hea Seung HS Han²

¹Department of Pediatrics, College of Medicine, Inha University, Incheon, Korea
¹Department of Pediatrics, College of Medicine, Inha University, Incheon, Korea
²Department of Pathology, College of Medicine, Inha University, Incheon, Korea
²Department of Pathology, College of Medicine, Inha University, Incheon, Korea

Correspondence Young Se YS Kwon ,Email: ysped@inha.ac.kr
Young Se YS Kwon ,Email: ysped@inha.ac.kr

Abstract

Centrinuclear myopathy, an uncommon condition, is one of the congenital myopathies. It is characterized by the presence of central nuclei of muscle cells which can be detected on electronmicroscopy. It is believed to arise as a result of maturational arrest with persistence of microtubes postnatally. We report a boy with generalized hypotonia and muscle weakness who was diagnosed as centrinuclear myopathy by muscle biopsy.

Keywords :Congenital myopathy, Centrinuclear