All issues > Volume 47(3); 2004

Original Article

Korean J Pediatr. 2004;47(3):294-303. Published online March 15, 2004.

Congenital Heart Disease in Jeju : Postnatal Incidence and Clinical Features

Jung Ha JH Lee¹, Gyu Hong GH Shim¹, Kyung Sue KS Shin², Jung Yun JY Hong², Yeoun Woo YW Kim², Seong Ho SH Kim³, Chung Il CI Noh¹

¹Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea
²Department of Pediatrics, Cheju National University College of Medicine, Jeju, Korea
³Department of Pediatrics, Halla General Hospital, Jeju, Korea

Correspondence Yeoun Woo YW Kim ,Email: yeonukim@cheju.ac.kr

Abstract

Purpose
: This is a retrospective descriptive study to determine the incidence of congenital heart disease(CHD) in Jeju and to estimate the suitability of the Jeju population as the subject for a regional birth cohort study.
Methods
: All patients with CHD diagnosed by two dimensional echocardiography in Cheju National University Hospital and Halla General Hospital from January 1999 to March 2003 were included in this study.
Results
: From April 1999 to March 2002, the crude incidence rate was 10.06 per 1,000 live births (236 cases/23,464 live births). Among the 236 cases, the proportion of each type was as follows : Ventricular septal defect(44.9%), atrial septal defect(21.2%), pulmonary stenosis(11.0%), patent ductus arterios us(9.3%), tetralogy of Fallot(3.4%), transposition of great arteries(2.1%), aortic stenosis(1.3%), hypoplastic left heart syndrome(1.3%), coarctation of aorta(0.8%), total anormalous pulmonary venous return(0.8%), tricuspid atresia(0.8%), heterotaxia(0.4%), single ventricle(0.4%), atrioventricular septal defect(0.4%), Ebstein anomaly(0.4%). The male to female ratio was 1 : 1.380(P=0.011). For unknown reasons, females showed significantly higher incidence in VSD(P=0.005) and PDA(P=0.019). Mortality rate was 0.34 per 1,000 live births. The types of VSD were 72.1% of perimembranous, 16.4% of trabecular muscular, 5.7% of subarterial, and 5.7% of unknown.
Conclusion
: This is the first regional study on the incidence of CHD in Korea. The incidence of CHD in Jeju was 10.06 per 1,000 live births. Most of our cases were VSDs and ASDs. Jeju would be a good subject for a regional cohort study in the future.

Keywords :Congenital heart disease, Incidence, Echo cardiography, South Korea, Congenital heart defect