All issues > Volume 47(4); 2004

Case Report

Korean J Pediatr. 2004;47(4):458-461. Published online April 15, 2004.

Neurofibromatosis Type 1 with Cerebellar Piloytic Astrocytoma

In-Sang IS Jeon¹, Jung Sun JS Kim¹, Ji Hye JH Kim², Na Rae NR Kim³

¹Departments of Pediatrics, Gachon Medical School, Inchon, Korea
²Departments of Diagnostic Radiology, Gachon Medical School, Inchon, Korea
³Departments of Pathology,Gachon Medical School, Inchon, Korea

Correspondence In-Sang IS Jeon ,Email: isjeon@ghil.com

Abstract

Neurofibromatosis type 1(NF1) is one of the most common inherited disorders, clinically characterized by caf -au-lait spots, Lisch nodules and neurofibromas. In addition, the affected individuals usually develop benign and malignant tumors of the nervous system. One of the most common tumors is the optic nerve glioma. NF1-associated glioma, however, rarely occurs in the cerebellum. Recently, we experienced a NF1-associated cerebellar pilocytic astrocytoma in an 11 years old girl. She has a family history of NF1 and multiple caf -au-lait spots over her whole body. We report herewith a case of NF1-associated cerebellar pilocytic astrocytoma with a brief review of related literature.

Keywords :Neurofibromatosis type 1, Astrocytoma