All issues > Volume 47(10); 2004

Case Report

Korean J Pediatr. 2004;47(10):1106-1109. Published online October 15, 2004.

A Case of Fulminant Hepatitis from Hepatitis A in a Child

Young Min YM Kim¹, Jae Sun JS Kim¹, Sun Hwan SH Bae², Dong Hoon DH Kim³

¹Department of Pediatrics, College of Medicine, Eulji University, Seoul, Korea
²Department of Pediatrics, College of Medicine, Eulji University, Seoul, Korea
³Department of Pathology, College of Medicine, Eulji University, Seoul, Korea

Correspondence Sun Hwan SH Bae ,Email: baedori@hanafos.com

Abstract

Fulminant hepatitis from hepatitis A in children is rare and has a low survival rate. We report a case of fulminant hepatitis from hepatitis A in a 12-year-old girl. The patient was admitted because of a three day history of fever, epigastric pain and vomiting. On her second hospital day, she had insomnia, anxiety, dysthesia, continuous fever, vomiting and nausea. In laboratory findings, decreased white blood cell and platelet count, markedly elevated serum aminotransferase levels, elevated serum bilirubin levels, prolonged prothrombin time and partial thromboplastin time were seen. Factor VIII appeared normal range. The histopathologic findings were necrosis in hepatic lobules, periportal necrosis, portal lymphocytic infiltration and fibrous portal expansion. We treated the patient with supportive care. After treatment, clinical manifestations and laboratory findings were improved.

Keywords :Hepatitis A, Fulminant hepatitis, Child