All issues > Volume 47(12); 2004

Case Report

Korean J Pediatr. 2004;47(12):1347-1350. Published online December 15, 2004.

A Case of Childhood Acute Lymphoblastic Leukemia with Monosomy 20 and Parotid Gland Involvement

Hae Rim HR Kim¹, Seung Ah SA Hong¹, Byung Kyu BK Choe¹, Heung Sik HS Kim¹, Jung Sook JS Ha², Dong Seok DS Jeon², Yu Na YN Kang³

¹Department of Pediatrics, Keimyung University, School of Medicine, Daegu, Korea
²Department of Laboratory Medicine, Keimyung University, School of Medicine, Daegu, Korea
³Department of Pathology, Keimyung University, School of Medicine, Daegu, Korea

Correspondence Heung Sik HS Kim ,Email: kimhs@dsmc.or.kr

Abstract

Hypodiploidy exists in 3-15% of patients with childhood acute lymphoblastic leukemia(ALL) and is associated with a poor prognosis. Monosomy 7 and monosomy 20 account for most karyotypic abnormalities in patients in whom whole chromosomes are lost and their incidences are rare. Parotid tumors in the pediatric age group are unusual and in 1996, there was a case of invasion of the parotid glands of ALL in a 6-year-old boy with swelling of both parotid glands. But invasion of acute lymphocytic leukemia to the parotid gland has not yet been reported in Korea. Here, we report a 33 month-old boy with swelling of both parotid glands who was diagnosed to have ALL with monosomy 20 & parotid gland invasion.

Keywords :ALL, Monosomy 20, Parotid gland