All issues > Volume 48(1); 2005

Case Report

Korean J Pediatr. 2005;48(1):97-100. Published online January 15, 2005.

A Case of Diffuse Panbronchiolitis Developing in Childhood

Jung Hoon JH You¹, Hyung Shin HS Lee¹, Kyung Yil KY Lee¹, Ja Hyun JH Hong¹, Mi Hee MH Lee¹, Byung Cheol BC Lee¹

¹Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea

Correspondence Hyung Shin HS Lee ,Email: leehs3@catho;ic.ac.kr

Abstract

Diffuse panbronchiolitis(DPB) is a chronic inflammatory airway disease predominantly affecting respiratory bronchioles, with distinct clinicopathological profiles. It was first described in 1966 by Yamanaka et al. The etiology of DPB is not yet clear, and the natural history of the disease is respiratory failure leading to cor pulmonale and ultimately death. But the long-term use of low-dose macrolide has proven to be highly effective in treating patients with DPB. Usual age at diagnosis is over 40. A few cases of DPB have been reported in Korea since 1992 but there have been no reports in children. We experienced a case of DPB in a 12-year-old girl. Therefore, we report the case with a brief review of the related literature.

Keywords :Diffuse panbronchiolitis , Children