All issues > Volume 48(3); 2005

Case Report

Korean J Pediatr. 2005;48(3):321-326. Published online March 15, 2005.

A Case of Multiple Giant Coronary Aneurysms with Large Mural Thrombus due to Kawasaki Disease in a Young Infant

Eun Na EN Choi¹, Jeoung Tae JT Kim¹, Yuria Y Kim¹, Byung Won BW Yoo¹, Deok Young DY Choi¹, Jae Young JY Choi¹, Jun Hee JH Sul¹, Sung Kye SK Lee¹, Dong Soo DS Kim¹, Young Hwan YH Park²

¹Department of Pediatrics, Cardiovascular Center, Yonsei University College of Medicine, Seoul, Korea
²Department of Cardiovascular Surgery, Cardiovascular Center, Yonsei University College of Medicine, Seoul, Korea

Correspondence Jae Young JY Choi ,Email: cjy0122@yumc.yonsei.ac.kr

Abstract

Kawasaki disease is an acute systemic vasculitis of unknown origin. Giant coronary aneurysm is one of the most serious complications, although peripheral artery vasculitis can produce life-threatening events. Myocardial ischemia and infarction can be caused by coronary artery stenosis, aneurysm, and stagnation of blood flow in coronary arteries which triggers thromboembolism. Atypical presentation in young infants often interferes with prompt diagnosis and timely treatment, resulting in poor outcomes. We describe a 3-month-old infant with multiple giant coronary aneurysms with flow stagnation, stenosis and large mural thrombus due to Kawasaki disease. He presented with a prolonged course of severe coronary involvement in spite of all measures to reduce coronary complications. Finally, surgical intervention was tried because of the worsening coronary artery abnormalities. The patient died of acute cardiorespiratory failure shortly after weaning from cardiopulmonary bypass.

Keywords :Mucocutaneous lymph node syndrome , Coronary aneurysm , Coronary thrombosis , Infant , Myocardial ischemia