All issues > Volume 48(3); 2005

Case Report

Korean J Pediatr. 2005;48(3):342-345. Published online March 15, 2005.

A Case of Neonatal Lupus Erythematosus Associated with Anti-U1RNP Antibodies

Byung-Hoon BH Ahn¹, Gu Chang GC Lee², Tae Young TY Yoon², Mi-Jung MJ Kim¹

¹Department of Pediatrics, College of Medicine, Chungbuk National University, Cheongju, Korea
²Department of Dermatology & Medical Research Institute, College of Medicine, Chungbuk National University, Cheongju, Korea

Abstract

Neonatal lupus erythematosus(NLE) is a distinct subset of lupus characterized by cutaneous findings, cardiac conduction defects, hepatic or hematologic abnormalities. These manifestations are associated with the presence of maternal auto-antibodies such as anti-SSA/Ro, anti-SSB/La, and rarely anti- RNP(U1RNP) antibodies. Cases of U1RNP antibody-positive NLE have somewhat atypical cutaneous manifestation without cardiac or systemic abnormalities. We report a case of cutaneous NLE associated with U1RNP antibodies.

Keywords :Neonatal lupus erythematosus , U1RNP antibody