All issues > Volume 48(6); 2005

Case Report

Korean J Pediatr. 2005;48(6):675-677. Published online June 15, 2005.

Prevention and Dissociation of the Platelet Aggregation in a Patient with EDTA-dependent Pseudothrombocytopenia by Supplementation of Kanamycin : A Case Report

In-sang IS Jeon¹, Sung Wan SW Yang¹

¹Department of Pediatrics, Gachon Medical School, Incheon, Korea

Correspondence In-sang IS Jeon ,Email: isjeon@ghil.com

Abstract

Pseudothrombocytopenia is usually associated with anticoagulant ethylene diaminetetraacetic acid (EDTA). The platelet clumping that occurs in EDTA-dependent pseudothrombocytopenia (EDPT) can sometimes be prevented by the use of other anticoagulants such as heparin or sodium citrate. As an alternative, we used kanamycin before or after the withdrawal of EDTA-anticoagulated blood in a 6-year-old boy with EDPT. Kanamycin used supplementarily during the differentiation of EDPT effectively prevented platelet clumping.

Keywords :Pseudothrombocytopenia , EDTA , Kanamycin