All issues > Volume 48(9); 2005

Medical Lecture Course

Korean J Pediatr. 2005;48(9):920-923. Published online September 15, 2005.

Epilepsy and Oxygen Free Radicals

Won Seop WS Kim¹

¹Department of Pediatrics, College of Medicine, Chungbuk National University, Cheongju, Korea

Correspondence Won Seop WS Kim ,Email: wskim@chungbuk.ac.kr

Abstract

Epilepsy is a neurological disorder from many molecular and biochemical responses. In the underlying mechanism, free radicals play an important role in seizure initiation and seizure-induced brain damage. Excessive production of oxygen free radicals and other radical species have been implicated in the development of seizures under pathological conditions and linked to seizure-induced neurodegeneration.

Keywords :Epilepsy , Oxygen free radicals