All issues > Volume 48(10); 2005

Original Article

Korean J Pediatr. 2005;48(10):1139-1142. Published online October 15, 2005.

Clinical and Epidemiologic Study of Kawasaki Disease in Children 8 Years of Age and Older

Yong Won YW Park¹, Ji Whan JW Han², In Sook IS Park³, Chang Hwi CH Kim⁴, Sung Ho SH Cha⁵, Jae Sook JS Ma⁶, Tae Chan TC Kwon⁷, Sang Bum SB Lee⁸, Chul Ho CH Kim¹, Heung Jae HJ Lee⁹, Yong Soo YS Yun¹⁰

¹Department of Pediatrics, College of Medicine, Inje University, Seoul Paik Hospital, Seoul, Korea
²Department of Pediatrics, College of Medicine, Catholic University, Seoul, Korea
³Department of Pediatrics, College of Medicine, University of Ulsan, Korea
⁴Department of Pediatrics, College of Medicine, Soonchunhyang University, Buchun, Korea
⁵Department of Pediatrics, College of Medicine, Kyunghee University, Seoul, Korea
⁶Department of Pediatrics, College of Medicine, Chonnam National University, Kwangju, Korea
⁷Department of Pediatrics, College of Medicine, Keimyung University, Daegu, Korea
⁸Department of Pediatrics, College of Medicine, Kyungpook National University, Daegu, Korea
⁹Department of Pediatrics, College of Medicine, Sungkyunkwan University, Seoul, Korea
¹⁰Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea

Correspondence Yong Won YW Park ,Email: yongpw@hanmail.net

Abstract

Purpose
: The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease(KD) in children 8 years of age and older.
Methods
: For the epidemiologic study of KD in Korea, data of total 15,692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of 211 KD patients 8 years of age and older were analyzed and compared with those of the KD patients less than 8 years of age.
Results
: 211 patients 8 years of age and older(1.3% of total KD patients) with the mean age of 9.8 years, included 142 cases aged 8-10 years, 42 cases aged 10-12 years, and 27 cases aged 12 years and older. The male-to-female ratio was 1.9 : 1, the recurrence rate was 3.8%, and the prevalence of cases in sibling was zero. Coronary arterial(CA) abnormalities were detected by echocardiography in 25.4% of the cases, including 7.6% of CA aneurysm cases. There was 1 case complicated by myocardial infarction.
Conclusion
: Comparing with the data of the KD patients less than 8 years of age, data of 211 patients 8 years of age and older showed significantly higher incidences of CA abnormalities(25.4% : 19.8%) and CA aneurysms(7.6% : 4.0%).

Keywords :Kawasaki disease , Mucocutaneous lymph node syndrome , Coronary aneurysm , Epidemiology , Child