All issues > Volume 48(11); 2005

Original Article

Korean J Pediatr. 2005;48(11):1193-1200. Published online November 15, 2005.

Clinical Entities and Etiology of Invasive Bacterial Infections in Apparently Healthy Children

Joon Ho JH Lee¹, Eun Kyoung EK Song¹, Jin A JA Lee¹, Nam Hee NH Kim¹, Dong Ho DH Kim², Ki Won KW Park³, Eun Hwa EH Choi¹, Hoan Jong HJ Lee¹

¹Department of Pediatrics, Seoul National University College of Medicine
²Cancer Center Hospital, Seoul, Korea
³National Police Hospital, Seoul, Korea

Correspondence Hoan Jong HJ Lee ,Email: hoanlee@snu.ac.kr

Abstract

ilus influenzae has been declined to 4% each from 23% and 14%, respectively, compared to previous study. S. agalactiae was the most common isolate in the infants ≤3 months. Among the infants and children aged 3 months to 2 years and children of 2-5 years, S. pneumoniae(57%, 52%, respectively, in each group) was the most common isolates followed by S. aureus(17% and 24%, respectively). S. aureus was the most common isolates(73%) in children >5 years. Primary bacteremia was the most common clinical diagnosis(27%). S. pneumoniae was responsible for 42% of primary bacteremia, 50% of meningitis, and 69% of bacteremic pneumonia and empyema. S. aureus accounted for 80% of bone and joint infections. The case fatality rate was 8.1% for all invasive infections.
Conclusion
: We reviewed frequency of bacterial agents of invasive infections in children. The data may be useful for pediatricians to select adequate empirical antibiotics in the management of invasive bacterial infections.

Keywords :Bacterial infections , Bacteremia , Meningitis , Streptococcus pneumoniae , Staphylococcus aureus