All issues > Volume 49(11); 2006

Case Report

Korean J Pediatr. 2006;49(11):1223-1226. Published online November 15, 2006.

Pyridoxine responsive sideroblastic anemia in a boy with mitral valve prolapse

June Seung JS Sung¹, Ki Hwan KH Kim¹, Dong Gyun DG Han¹, Mi Jeong MJ Kim¹, Young Kook YK Cho¹, Hae Yul HY Chung¹, Hee Jo HJ Baek¹, Jae Sook JS Ma¹, Hoon H Kook¹, Tai Ju TJ Hwang¹

¹Department of Pediatrics, Hwasun Chonnam National University Hospital Chonnam National University Me

Correspondence Hoon H Kook ,Email: hoonkook@chonnam.ac.kr

Abstract

Sideroblastic anemia is a rare, heterogeneous group of disorders characterized by hyperferremia, microcytic hypochromic anemia, and bone marrow erythroid hyperplasia with the presence of numerous ringed sideroblasts. We describe herewith the case of a rare coincidence of sideroblastic anemia and mitral valve prolapse with resultant regurgitation in a 2-year-old boy. In addition to the inherent propensity for the development of cardiac dysfunction in sideroblastic anemia due to transfusion-associated myocardial iron overload and chronic anemia, a coincidence of MVP will further increase the likelihood of the morbidity or mortality of th patient. in this patient. After response to pyridoxine, the patient remains in good condition with stable hemoglobin levels.

Keywords :Sideroblastic anemia , Pyridoxine , Mitral valve prolapse