All issues > Volume 50(6); 2007

Case Report

Korean J Pediatr. 2007;50(6):580-584. Published online June 15, 2007.

A case of childhood relapsing/remitting multiple sclerosis and interferon β-1b treatment in a Korean patient

Hyun Seok HS Kim¹, Won Deok WD Lee¹, Jun Hwa JH Lee¹, Kyung Lae KL Cho¹

¹Department of Pediatrics, College of Medicine, Sungkyunkwan University Masan Samsung Hospital, Masan, Korea

Correspondence Jun Hwa JH Lee ,Email: ljh3643@hanmail.net

Abstract

Multiple sclerosis (MS) is a demyelinating disorder that affects discrete areas of the CNS, including the optic nerves, in a quite variable relapsing-remitting fashion over a prolonged period of time. Although MS is usually considered to be a disease that affects peoples in early to middle adulthood, children do develop multiple sclerosis. The frequency of MS onset before the age of 15 years is 2.7-5% of all cases, while MS onset during infancy and early childhood was observed to be 0.2- 0.7% of all cases. We report here on a Korean case of a relapsing-remitting MS female child who was treated with four rounds of intravenous methylpredinsolone pulse therapy and preventive Interferon-β-1b (Betaferon ).

Keywords :Multiple Sclerosis, Optic neuritis, Interferon-β-1b (Betaferon )