All issues > Volume 51(4); 2008

Original Article

Korean J Pediatr. 2008;51(4):401-408. Published online April 15, 2008.

Complications of transcatheter closure of atrial septal defects using the amplatzer septal occluder

Seo Jin SJ Jea¹, Hyo Jin HJ Kwon¹, Gi Young GY Jang¹, Jae Young JY Lee², Soo Jin SJ Kim², Chang Sung CS Son¹, Joo Won JW Lee¹

¹Departments of Pediatrics, College of Medicine, Korea University, Ansan, Korea
²Departments of Pediatric Cardiology, Sejong Heart Institute, Sejong General Hospital, Bucheon, Korea

Correspondence Gi Young GY Jang ,Email: jgynhg@dreamwiz.com

Abstract

Purpose
: Transcatheter closure of atrial septal defects (ASD) is currently established therapy as an alternative to surgery. But rarely, complications are reported in some studies. We report early and intermediate term complications associated with transcatheter closure of atrial septal defects using the Amplatzer septal occluder (ASO).
Methods
: From June 2003 to May 2006, 64 patients underwent transcatheter closure of secundum ASD or patent foramen ovale using the ASO. The ratio of male to female was 1:2.4, the median age was 17 years (range: 2.6-64 years) and their median weight was 47.5 kg (range: 2.6-64 kg).
Results
: The median diameter of ASD measured with transthoracic or transesophageal echocardiography was 15 mm (range: 6-28 mm), the median balloon stretched diameter was 18 mm (range: 6.5-34 mm), and the median size of device was 19.5 mm (range: 6-36 mm), was little difference with balloon stretched diameter. There were 10 cases of complications: arrhythmia (2), device malformation (2), aorta to right atrial fistula (1), hemolytic anemia (1), mitral valve encroachment (1), malposition (1), residual shunt (1), and inferior vena cava perforation (1).
Conclusion
: Transcatheter closure of ASD using ASO is effective and safe therapy. However, significant complications such as aorta to atrial fistula, atrial erosion, or device embolization can happen, so an appropriate selection of patient and device in relevance to size and anatomy of ASD is important for successful closure.

Keywords :Atrial septal defect, Transcatheter closure, Complications