All issues > Volume 51(8); 2008

Original Article

Korean J Pediatr. 2008;51(8):861-867. Published online August 15, 2008.

Comparison of occurrence rate of the epileptiform discharge between awake EEG and sleep EEG in childhood epilepsy

Yu Jin YJ Jung¹, Kyoung Ah KA Kwon², Sang Ook SO Nam²

¹Department of Pediatrics, Dongkang Hospital, Ulsan, Korea
²Department of Pediatrics, College of Medicine, Pusan National University, Busan, Korea

Correspondence Sang Ook SO Nam ,Email: weareone@pusan.ac.kr

Abstract

Purpose
: We carried out this study to determine if there is any difference in the occurrence rate of the epileptiform discharge between awake EEG and sleep EEG and if there are any factors influencing on the occurrence rate of EEG.
Methods
: This study included 178 epileptic children who had visited neurology clinic of the department of pediatrics, Pusan National University Hospital from July 2005 to July 2006. The medical and EEG records of these children who had had both awake EEG and sleep EEG were reviewed. We analysed the occurrence rate of the epileptiform discharge between awake EEG and sleep EEG. We investigated the related clinical factors which included sex, seizure types, underlying causes, age at first seizure, antiepileptic drug (AED) medication, age at recording, and background activity.
Results
: Among 178 epileptic children, 91 patients (51.1%) showed epileptiform discharge in awake or sleep states, 10 patients (11.0%) abnormal only in awake, 40 patients (44.0%) abnormal only in sleep, 41 patients (45.0%) abnormal in both awake EEG and sleep EEG. The occurrence rate of sleep EEG was 81 of 178 patients (45.5%) which was more than that of the awake EEG (28.7%) (P<0.001). The occurrence rate of sleep EEG is more than that of the awake EEG regardless of sex and underlying causes. But there is no significant difference from awake EEG and sleep EEG in finding the epileptiform discharge in the patient with generalized seizure, younger than 5 years old at first seizure, younger than 10 years old at recording, no antiepileptic medication, and abnormal background activity.
Conclusion
: The sleep EEG is thought to be more helpful in the diagnosis of childhood epilepsy.

Keywords :Occurrence rate, Epilepticform discharge, Eelectroencephalogram