All issues > Volume 52(1); 2009

Case Report

Korean J Pediatr. 2009;52(1):129-132. Published online January 15, 2009.

Changes in N-terminal pro-B-type natriuretic peptide in a neonate with symptomatic isolated left ventricular noncompaction

Ji Hyeun JH Song¹, Yeo Hyang YH Kim¹, Chun Soo CS Kim¹, Sang Lak SL Lee¹, Tae Chan TC Kwon¹

¹Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea
¹Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea
¹Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea
¹Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea
¹Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea

Correspondence Yeo Hyang YH Kim ,Email: kimyhped@hanmail.net

Abstract

We describe here our experience with a neonate presenting with cyanosis, grunting, and cardiomegaly, who was diagnosed with isolated left ventricular noncompaction (IVNC) by echocardiography. The patient had high levels of N-terminal pro-B-type natriuretic peptide (NT pro-BNP) and symptoms of heart failure including poor feeding and tachypnea. During the period in which NT pro-BNP levels steadily increased, the patient suffered sudden cardiac arrest despite heart failure management. Following cardiopulmonary resuscitation, cardiac arrest was resolved, NT pro-BNP levels decreased, and all symptoms showed improvement. We consider that assessment of NT pro-BNP with cardiac functional analysis using echocardiography could help in the prediction of disease progress in IVNC.

Keywords :Newborn, Myocardium, Natriuretic peptide, Brain