All issues > Volume 53(1); 2010

Case Report

Korean J Pediatr. 2010;53(1):106-110. Published online January 15, 2010.

A case of hippocampal sclerosis diagnosed as cortical dysplasia due to preoperative brain MRI finding

Jun Seok JS Lee¹, Kyo Ryung KR Kim¹, Jeong Tae JT Kim¹, Min Jung MJ Choi¹, Young Mock YM Lee¹, Heung Dong HD Kim¹, Joon Soo JS Lee¹, Dong Seok DS Kim², Tae Seong TS Kim³

¹Department of Pediatrics, Severance Children`s Hospital, Yonsei University College of Medicine, Seoul, Korea
²Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea
³Department of Pathology, Yonsei University College of Medicine, Seoul, Korea

Correspondence Joon Soo JS Lee ,Tel: +82.2-2228-2063, Fax: +82.2-393-9118, Email: joonsl96@yuhs.ac

Abstract

Hippocampal sclerosis (HS) is one of the most common features of intractable temporal lobe epilepsy. Generally it can be identified through brain magnetic resonance imaging (MRI) with high degree of sensitivity and specificity. Typical brain MRI findings of HS are hippocampal atrophy with hyperintense signal confined to the lesion. On the other hand cortical dysplasia exhibits blurring of the gray-white matter junction and abnormal white matter signal intensity. We present a case where preoperative brain MRI strongly suggested the presence of diffuse cortical dysplasia in the left temporal lobe but postoperative pathology revealed the temporal lesion to be unremarkable except for hippocampal sclerosis.

Keywords :Hippocampus, Cortical dysplasia, Epilepsy, Surgery, MRI