All issues > Volume 34(11); 1991

Original Article

J Korean Pediatr Soc. 1991;34(11):1573-1580. Published online November 30, 1991.

A case of primary hepatocellular carcinoma following vertical transmission of hepatitis B virus in a child.

Soo Kyoung Lee¹, Ki Sup Chung¹, Sun Won Hong², Chan Il Park²

¹Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea
²Department of Pathology, Yonsei University College of Medicine, Seoul, Korea

Received: June 4, 1991;  Accepted: July 26, 1991.

Abstract

Authors experienced a case of primary hepatocellular carcinoma in a 7 year 9 month old male patient, who was admitted to our hospital due to abdominal pain on right upper quadrant and anorexia during last two months. On family history, his mother was HBs Ag and HBe Ag carrier. On past history, he was admitted to a hospital due to persistant jaundice at 2 months of age, diagnosed as vertical trasmission of hepatitis B virus. At that time, his viral marker study reveraled HBs (+j, Anti HBc (+), HBe Ag(+), Anti HBs (—) and Anti HBe (—). There after, he didn’t have OPD follow up. Physical examination on admission revealed massive hepatosplenomegaly. Diagnostic confirma- tion of primary hepatocellular carcinoma was made by liver scan, abdominal ultrasonography, abdominal CT scan, and needle aspiration biopsy on liver under ultrasono guide.

Keywords :Primary hepatocellular carcinoma;Hepatitis B virus;Vertical transmission