All issues > Volume 34(11); 1991

Original Article

J Korean Pediatr Soc. 1991;34(11):1565-1572. Published online November 30, 1991.

Epidemics of aseptic meningitis in Seoul area during 1989-90.

Eun young Cho¹, Mi Koo Kang¹, Soo Jong Hong¹, Ki Soo Kim¹, Young Seo Park¹, In Sook Park¹, Hyung Nam Moon¹, Chang Yee Hong¹

¹Department of Pediatrics, College of Medicine, Ulsan University, Seoul, Korea

Received: June 25, 1991;  Accepted: July 4, 1991.

Abstract

We performed clinical and virological studies on 200 children with aseptic meningitis who had been admitted to the department of Pediatrics, Asan Medical Center from June, 1989 to August, 1990. The results were as follows; 1) There were total of 236 meningitis cases during this period, 13(5.5%) with bacterial meningitis, 3(1%) with tuberculous meningitis, 220(93.2%) with aseptic meningitis. Am이lg aseptic meningitis, 20(8.5%) were mumps meningitis. 2) Aseptic meningitis occurred mostly in June, July, and August. It affected patients without respect to their ages, but the male-to-female ratio was 3.2 to 1. 3) Most patients suffered from fever, vomiting, and headache. Facial palsy, paralysis, neurogenic bladder, transverse myelitis, and SIADH were observed in a few cases. Most recovered without neurological sequelae except 3 patients (1.4%). 4) The causative agent seemed to be Enterovirus 71 during the period from April, 1990 to June, 1990 when Hand-Foot-Mouth disease was prevalent, and thereafter Echovirus 30 was thought to be main causative agent according to the serologic study, spinal fluid culture of enterovirus and clinical features.

Keywords :Aseptic Meningitis;Enterovirus