All issues > Volume 34(10); 1991

Original Article

J Korean Pediatr Soc. 1991;34(10):1346-1355. Published online October 31, 1991.

Clinical analysis on newborn infants treated with mechanical ventilation.

Yeon Sim Kim¹, Dae Ho Choi¹, Cheol Woo Park¹, Yeon Kyun Oh¹

¹Department of Pediatrics, College of Medicine, Won-Kwang University, Iri, Korea

Received: March 4, 1991;  Accepted: May 13, 1991.

Abstract

Clinical analysis of 48 neonates who treated with Mechanical ventilation in NICU at Won-Kwang University Hospital from February 1987 to July 1990 was performed. The results were as follows; 1) According to diagnostic categories, hyaline membrane disease was the most common in 26 cases (54.2%), and then postasphyxia syndrome 10cases (20.8%), apnea of prematurity 3cases (6.2%), sepsis 3 cases (6.2%)，in their order. 2) 29 cases (60.4%) were bom at WUH and others were bom elesewhere, and male to female ratio was about 1.4:1. 3) Premature infants below 37 wks of gestational age were 32 cases (66.7%), and hyaline membrane disease were premature in 25 cases (96.2%). 4) Low birth weight infants below 2,500 gm were 36 cases(75%) and very low virth weight infants below 1,500gm were 14cases (29.2%). In 26 cases of hyaline membrane disease, infants below 2,500 gm were alll and below 1,500gm were 11 cases (42.3%). 5) According to selected mode of mechanical ventilation, CPAP mode was used in 7 cases (14.6%) and IPPB in 41 cases (85.4%). Assist ventilation was initiated before 24 hrs of age in 44 cases (91.7%) and in total duration of mechanical ventilation, 36 cases (75.0%) were below 3 days and 5 cases (10. 4%) above 7 days. 6) Complications were seen during mechnaical ventilation were infection (20.8%) including sepsis and pneumonia, extrapulmonary air leaks (14.6%), intracranial hemorrhage (12.5%), in their order. 7) Total survival rate was 35.4%. For each diagnostic categories, the survival rate in hyaline membrane disease was 30.8%, postasphyxia syndrome 30% and apnea of prematurity 100%. The survival rate in infants less than 999 gm was 0%, 1,000〜 1,499 gm 60%, 1,500—1,999 gm 41.7% and more than 2,500 gm 27.3%, and in infants of gestational age below 28 wks was 12.5%, 29〜3 wks 50%, 33-36 wks 20%. 8) Follow up observations were performed in 17 survived infants for the period of 3 months to 3 years and long term sequalaes were observed in 5cases (29.4%) as spastic quadriplegia, seizure disorder, bronchopulmonary dysplasia, delayed development and retinopathy of prematurity.

Keywords :Mechanical ventilation;Neonate