All issues > Volume 34(9); 1991

Original Article

J Korean Pediatr Soc. 1991;34(9):1299-1304. Published online September 30, 1991.

A case of nephrogenic diabetes insipidus due to vesicoureteral reflux.

Yong Bae Suh¹, Jong Yul Jeon¹, Sung Ho Cha¹, Byoung Soo Cho¹, Chang Il Ahn¹

¹Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea

Received: March 11, 1991;  Accepted: May 31, 1991.

Abstract

Nephrogenic diabetes insipidus is a disorder characterized by polydipsia and polyuria resulting from failure of the renal tubules and collecting ducts to respond to antidiuretic hormone despite elevated blood levels of antidiuretic hormone. We experienced a case of nephrogenic diabetes insipidus in 13 months-old girl probably secondary to vesicoureteral reflux grade IV. The clinical manifestations were extreme thirst, polydipsia and polyuria. Family history was nonspecific and laboratory findings revealed urinary concentration defect by water deprivation test and pitressin test. But urinalysis revealed normal specific gravity. Vesicoureteral reflux was corrected by ureteroneocystostomy. In conclusion, when patient complaints of polydipsia and polyuria, water deprivation test and pitressin test are mandatory even urinary specific gravity is within normal limit.

Keywords :Nephrogenic diabetes insipidus;Vesicoureteral reflux;Urinary tract infection