All issues > Volume 34(8); 1991

Original Article

J Korean Pediatr Soc. 1991;34(8):1086-1092. Published online August 31, 1991.

The relationship between diuresis and pulmonary function in respira- tory distress syndrome of the newborn.

Eun Ae Park¹, Yung Sook Ko¹, Gyoung Hee Kim¹

¹Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul, Korea

Received: March 15, 1991;  Accepted: April 4, 1991.

Abstract

The purpose of this study was to determine the relationship between improvement of pulmonary, function and diuresis in respiratory distress syndrome. This study was based on 24 cases of RDS infants admitted in NICU of Ewha Womans University from January 1988 to December 1990. The results were as follows. 1) Mean birth weight of study cases was 2.11 kg with gestational age between 29〜39 weeks. 2) Maximum FiO2 (inspired oxygen concentration) of mechanical ventilator was between 0.3 to 1. 0 and maximum respiratory rate was between 40~90 breaths per minute and maximum PEEP (peak end expiratory pressure) was 3—9 CmH20. 3) Mean age at onset of diuresis was 27.5 hours of postnatal age with maximum diuresis at 44.2 hours. 4) After diuresis, changes of alveolo-arterial oxygen gradient, inspired oxygen gradient, peak end expiratory pressure and respiratiory rate were statistically significant. On the basis of our observations, we conclude that the increase in urine output precedes the recovery of pulmonary function in infants treated with mechanical ventilation for RDS.

Keywords :RDS (respirator distress syndrome);Diuresis;Pulmonary function