All issues > Volume 34(6); 1991

Original Article

J Korean Pediatr Soc. 1991;34(6):849-856. Published online June 30, 1991.

A case of Bartter's syndrome.

Kyu Young Lee¹, Byoung Soo Cho¹, Hah Young Lee², Jay Bernstein³

¹Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea
²Department of Pediatrics, Dong Inckeon Gil Hospital, Incheon, Korea
³Department of Anatomic Pathology, William Beaumont Hospital, Michigan, U.S.A.

Received: August 2, 1990;  Accepted: November 6, 1990.

Abstract

Bartter’s syndrome in characterized by renal potassium wasting, hypokalemic alkalosis, hyper- reninemia, normal blood pressure and resistance to the blood pressure augmenting effect of angioten- sin, accompanied by often hypomagnesemia and increased production of certain renal prostaglandins. The primary defect in this rare disorder is considered to be a renal tubular dysfunction. We had experienced a case of Bartter’s syndrome in 9 months old male infant, who had a dramatic response by indomethacin. In addition to case report, brief review of related literatures was done.

Keywords :Bartter's syndrome;Indomethacin