All issues > Volume 34(5); 1991

Original Article

J Korean Pediatr Soc. 1991;34(5):715-719. Published online May 31, 1991.

A case of metastatic neuroblastoma to brain.

Sang Wook Choi¹, Mee Jeong Lee¹

¹Department of Pediatrics, Korea Cancer Center Hospital, Seoul, Korea

Received: September 19, 1990;  Accepted: November 17, 1990.

Abstract

Metastatic neuroblastoma to whole bones and brain generally has been considered incurable, but some reports have been published with good and partial response after initial chemotherapy followed by second-look operation. But the long term survival is dismal. Recently we experienced a case of metastatic neuroblastoma to brain without neurologic symptoms confirmed by computed tomograpy, who had multiple bony metastases including skull. The whole metastatic lesions to bones and brain have been clearing up after 3 cycles of multi-agent chemotherapy. So we suggest multi-agent high dose chemotherapy to the patients with poor prognosis.

Keywords :Neuroblastoma stage IV;Brain metastasis