All issues > Volume 34(4); 1991

Original Article

J Korean Pediatr Soc. 1991;34(4):473-479. Published online April 30, 1991.

Predictors of neurologic handicap in hypoxic ischemic encephalopathy.

Seung Tae Kim¹, Gui Ran Kim¹, Byung Hak Lim¹, Sang Geel Lee¹, Im Ju Kang¹

¹Department of Pediatrics, Fatima Hospital, Taegu, Korea

Received: July 31, 1990;  Accepted: November 10, 1990.

Abstract

Retrospective follow up studies were done in 52 term infants who were treated at the nursery in Taegu Fatima Hospital, for clinical evidence of Hypoxic ischemic enecphalopathy (stage II). All children were followed for a minimum of 6 months. Factors that significantly correlated with prognosis included 5-minute Apgar scores, the age at the onset of the seizures, the EEG and the initial brain CT. (1) Of seven with the severe asphyxia (Apgar score 0 〜3》，six showed the abnormal neurologic handicap on follow up study (p<0.01). (2) Of eleven with the occurrence of seizure within 12 hours, seven showed the abnormal neurologic handicap (p<0.01). (3) Of fifteen with the abnormal EEG finding, ten shwoed the abnormal neurologic handicap (p< 0.01). (4) Of sixteen with the abnormal brain CT finding, eleven showed neurologic handicap on follow up study. Especially nine with the extensive area of hypodensity of the white and gray matter were severely handicapped (p<0.01).

Keywords :Hypoxic ischemic encephalopathy;Predictors of Neuroloogic handicap