All issues > Volume 34(3); 1991

Original Article

J Korean Pediatr Soc. 1991;34(3):388-397. Published online March 31, 1991.

Detection of antigen of RSV and clinical considerations on epinephrine response in wheezy infancy.

Gui Ran Kim¹, Seoung Tae Kim¹, Hyang Suk Hyun¹, Sang Geel Lee¹, Im Ju Kang¹, Sei Yun Jung²

¹Department of Pediatrics, Fatima Hospital, Daegu, Korea
²Department of Clinicopathology, Fatima Hospital, Daegu, Korea

Received: July 24, 1990;  Accepted: October 17, 1990.

Abstract

Clinical studies were made on 126 cases of wheezing infants, who had been admitted to the department of pediatrics, Fatima Hospital, from June 1988 to May 1989. The nasal discharge of patients were examined for detection of antigen of RSV by ELISA method and then we compared RSV antigen positive group with RSV antigen negative group on aspects of epinephrine response and atopic characteristics. The results as follows 1) The antigen of RSV was detected in 19 cases (15.1%) 2) The response to epinephrine was higher in RSV antigen negative group and higher response rate was observed in patients greater than 12 months of age 3) There was no significant difference in family history of atopy, past history of infantile eczema, level of total serum IgE, and skin test to histamine between RSV antigen positive group and negative group. 4) Recurrence of wheezing was higher in RSV antigen negative group, and highest response rate was noted in epinephrine responders of RSV antigen negative group. There was no significant difference in atopic characterics between recurrent and nonrecurrent group, and higher recurrence rate was observed in group, who had been positive skin test to histamine more than 3 mm and family history of atopy.

Keywords :Antigen of RSV;Epinephrine Response;Wheezy Infancy