All issues > Volume 34(2); 1991

Original Article

J Korean Pediatr Soc. 1991;34(2):273-280. Published online February 28, 1991.

Two cases of islet cell hyperplasia with nesidioblastosis.

Myeong Ku Cho¹, Kyeong Bae Park¹, Gyu Bum Cho¹, Dong Hwan Lee¹, Sang Jhoo Lee¹, D.H Lee²

¹Department of Pediatrics, College Medicine, Soon Chun Hyang University, Seoul, Korea
²Department of Clinical Pathology , College Medicine, Soon Chun Hyang University, Seoul, Korea

Received: August 13, 1990;  Accepted: September 28, 1990.

Abstract

Hypoglycemia due to Hyperinsulinism is associated with nesidioblastosis, islet cell hyperplasia or adenoma. We experienced two newborn infants suffering from recurrent attacks of hypoglycemia, they were underwent a subtotal pancreatectomy for suspected islet cell dysmaturation syndrome. No tumor was found, but histology revealed islet cell hyperplasia and nesidioblastosis. After surgery one case who was treated with diazoxide, had persistent hypoglycemia but the other showed normal glucose value.

Keywords :Islet Cell Hyperplasia;Nesidioblastosis