All issues > Volume 33(12); 1990

Original Article

J Korean Pediatr Soc. 1990;33(12):1735-1740. Published online December 31, 1990.

Osteogenic Sarcoma as Second Malignant Neoplasm After Treatment of Retinoblastoma.

Ja Young Kim¹, Moon Whan Lee¹, Ju Hyung Kim¹, Pyoung Han Hwang¹, Jung Soo Kim¹

¹Department of Pediatrics, College of Medicine, Chonbuk National University, Chonju, Korea

Received: July 5, 1990;  Accepted: September 28, 1990.

Abstract

The improvement in survival for childhood cancer has been achieved through the use of multiple- agent chemotherapy and radiotherapy. However, one of the limitations to quality and length of survival has been the development of second malignant neoplasm. We exprienced a case of second malignant neoplasm in 13-year-old boy who developed osteogenic sarcoma after successful treatment of retinoblastoma. At 3 years of his age, he was diagnosed as retinoblastoma and managed by enucleation of left eye at a university hospital in Seoul. Ten years later, painful swelling was noted on the right ankle joint. Histopathological findings revealed osteblastic osteogenic sarcoma and metastasis to lung was detected on chest X-ray. He received multiple-agent chemotherapy for one time. Thereafter, he was lost to follow-up and expired 9 months after diagnosis of second mailgnant neoplasm.

Keywords :Second malignant neoplasm, Osteogenic sarcoma, Retinoblastoma