All issues > Volume 33(10); 1990

Original Article

J Korean Pediatr Soc. 1990;33(10):1413-1417. Published online October 31, 1990.

A Case of Lissencephaly with West Syndrome.

Byoung Yul Lim¹, Ji Ho Song¹, Sa Jun Chung¹, Chang Il Ahn¹

¹Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea

Received: May 12, 1990;  Accepted: July 24, 1990.

Abstract

Neuronal migrational disorders of the brain represent abnormalities in the formation of the neocortex caused by faulty migration of the subependimal neuroblasts. Lissencephaly is a rare congenital anomaly representing an arrest of brain development before the third or fourth month of gestaional age. The most common clinical findings were seizure, delayed development, failure to thrive and hydrocephalus. The authors experienced a case of lissencephaly with West syndrome. Diagnosis was made by the characteristic CT, MRI and EEG findings.

Keywords :Lissencephaly, West syndrome