All issues > Volume 33(9); 1990

Original Article

J Korean Pediatr Soc. 1990;33(9):1231-1236. Published online September 30, 1990.

Relationship between anaphylactoid purpura and Beta-Hemolytic Streptococcal Infection.

Ji Eun Lee¹, Young Sook Kang¹, Joon Sik Kim¹, Sung Ho Kim¹, Chin Moo Kang¹

¹Department of Pediatrics, School of Medicine, Keimyung University, Taegu, Korea

Received: May 25, 1990;  Accepted: July 31, 1990.

Abstract

Relationship between anaphylactoid purpura and beta-hemolytic streptococcal infection was obser- ved and analyzed through clinical manifestation and labortory findings in 146 cases of allergic purpura, hospitalized at Dongsan hospital, Keimyung University during the period from January, 1981 to May, 1987. The following results were obtained. 1) The age distribution of anaphylactoid purpura showed a peak incidence between 2 to 7 years of age and male preponderance was observed with male to female ratio of 1.6 to 1. 2) The disease were found mostly in March and April(23.9%), also in October and November (23. 2%). 3) The clinical manifestations showed in skin (100%)，gastrointestinal tract (73.2%), joint (61.6%), kidney (30.1%) respectively. 4) The preceding illness was shown in 29.5% of the cases and respiratory tract infections were more prevalent, noted in 22.5%. 5) As for the laboratory finding, Ig A was increased in 54.2% of cases, Ig E in 39.2% and eosinophil count in 14.3% and C3 level was decreased in 3.4% of cases. 6) ASO titer (over 333 todd unit) was elevated in 23.4% of the cases and beta-hemolytic streptococci was found in one case (0.7%) for throat culture. 7) Elevation of ASO titer was present in 25% of the cases who had renal involvement. The results obtained in this study hardly support a causal relationship between anaphylactoid prupura and the beta-hemolytic streptococcal infection.

Keywords :Anaphylactoid purpura, Beta-hemolytic streptococcal infection