All issues > Volume 33(9); 1990

Original Article

J Korean Pediatr Soc. 1990;33(9):1223-1230. Published online September 30, 1990.

Human Rotavirus Antigen in Respiratory Secretion.

Kyung Min Lee¹, Won Chul Lee¹, Kook Shin Chang¹, Mee Kyung Chjang¹, Woo Tack Kim¹, Dong Jin Lee¹

¹Department of Pediatrics, Ulsan Dong-Kang Hospital, Ulsan, Korea

Received: January 29, 1990;  Accepted: March 31, 1990.

Abstract

A clinical study was carried out on 33 diarrhea patients to determine the frequency and degree of respiratory symptoms and signs in patients with gastroenteritis who had HRV antigen in respira- tory secretion. We devided study group into two: One was 11 children who had HRV antigen in respiratory secretion but did not have in diarrheal stool and the other was 22 children who had HRV antigen in respiratory secretion and diarrheal stool both. Control group was 34 children who had HRV antigen in diarrheal stool but hadn’t in respiratory secretion. The HRV antigen was determined by latex agglutination test. All patients included in this study were admitted to the pediatric department of Ulsan Dong-Kang Hospital from November, 1988 to January, 1989. The following results were obtained; 1) There was no significant difference in age distribution, sex ratio, duration from onset of illness to admission and duration of hospital admission between study group and control one. 2) Coughing & rhinitis were noted on admission in two study groups 100% & 72.7% respectively, which were higher than those of control group(p<0.005). Wheezing, rhonchi, stridor & rale were noted on admission in two study groups 45.5% & 40.9% respectively, which were higher than those of control groups(p<0.005). 3) Duration of coughing in two study groups was 15.2 % ± 7.3 days & 12.1 % ± 5.8days respectively, which was longer than those of control group(p<0.00). Duration of rhinitis in two study groups was 13.1±3.1 days & 11.4±4.3 days respectively, which was also longer than those of control group(p< 0.005). 4) Duration of diarrhea in two study groups was 8.9±4.6 days & 7.5±3.3 days respectively, which was longer than those of control groups(p<0.05). 5) Out of associated illness & complication, bronchiolitis in two study groups was 36.4% both, pneumonia was 36.4% & 13.6% each other respectively, which were higher than those of control group(p< 0.001). 6) There was no significant difference in the tate of pulmonary infiltration on chest X-ray between study & control one.

Keywords :Human rotavirus antigen, Respiratory secretion