All issues > Volume 33(8); 1990

Original Article

J Korean Pediatr Soc. 1990;33(8):1155-1158. Published online August 31, 1990.

Two Cases of Cerebral Gigantism (Sotos Syndrome).

Hee Jeung Ahn¹, Young Tae Kim¹, In Hoon Seol¹, Jeh Hoon Shin¹

¹Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea

Received: February 8, 1990;  Accepted: May 9, 1990.

Abstract

Cerebral gigantism, the condition described by Sotos et al in 1964, consists of excessively rapid growth rating from infancy followed by a normal growth rate, acromegalic features, and a non- progressive neurological disorder manifested by clumsiness. The etiology of cerebral gigantism is not clear. Increased growth hormone levels have not been documented and somatomedin activity was found to be within normal range as yet reported. We experienced two cases of cerebral gigantism in 1 10/12 and 7 year old girls with a brief review of literatures.

Keywords :Cerebral Gigantism